We Can Make the Microbes in Yo Belly Make Shit & it Will Save Ya!
Can the critters in your bowels help your health? The critters, also known as your micro biome contributes significantly to your health. The micro-biome is a complex ecosystem of microbes that live amongst and sometimes even in your cells. The location in your body will determine the distinct communities found, for example your mouth, vagina and gut will have completely different flora.
New research from The Rockefeller University and the Icahn School of Medicine at Mt. Sinai suggests there is a method to genetically engineer gut bacteria to produce molecules that have the potential to treat certain disorders by altering human metabolism. WHAT? One example they have been successful with in mice is lowering blood glucose levels.
Well, Scientists took advantage of a cells way of communicating. They utilized the lock-and-key relationship of ligands and the receptors that reside on the membranes of human cells. This interaction produces a specific biological effect. Specifically in this case, the engineered bacteria produced a specific ligand that binds with the GPCRs or G-protein-coupled receptors. These receptors play an important role in many pathways and thus were a prime target.
DID YOU SEE HOW I JUST USED THUS FLUENTLY?
In their experiment they engineered a bacteria to create a ligand, specifically N-acyl amides. These bind to GPR 119 and is involved in appetite and glucose regulation.
Metabolic Diseases, what are they and how can this help?
Metabolic diseases are chemical reactions that disrupt the bodies metabolic process such as the ability to breakdown, process and absorb food are referred to as metabolic disorders. Examples of these are diabetes like the aforementioned, galactosemia (impaired break down of sugar galactose), phenylketonuria (deficiency in enzyme PAH can result in mental retardation), Glycogen Storage (leads to low blood sugar), and many many more.
This is going to be pretty rad. At the rate genetic engineering is going we should have the lifespan of a vampire in no time :D Now about these ominous wrinkles haha……
WHAT DO YOU THINK! Did I get anything wrong? What did I miss? Comment below :)