Zombie Cells are Killing You ! AHHHHHHHH Tick-tock, tick-tock
Zombie cells are killing you ! AHHHHHHHH
We accumulate cells called senescent cells which are basically microscopic zombies. They are normal ploid cells that just stop dividing. These dudes and dudettes tend to vomit proteins by the hundreds and send anti-death pathways into hyperdrive. Replicative senescence is produced when the telomeres are by far too short and during the replicative process they chomp on your precious DNA, damaging it. This can be brought on by other things such as reactive oxygen species or activation of oncogenes and cell-cell fusion (these forms are not caused by the shortening of telomere length). As you age these cells accumulate in your tissues, organs.
Studies in mice found that by removing these zombie like cells the mice had restored fitness, fur density and kidney function. In another study they found it to also improve lung disease, mend damaged cartilage AND appear to extend the lifespan of these furry friends.
Just by removing the zombies you stimulate new tissue production. What a find! The new anti aging elixir? Getting rid of the the old non functioning ones. Research underway on “the magic bullet” pill, OF COURSE!
Things that have been found to help the clearing away process is Spermidine (wheat germ, dried soybean, 1yr old cheddar, mushrooms, rice bran, chicken liver etc wiki has more) and resveratrol (This is a plants natural assassin for any pathogens or physical damage and you can get your dose in red wine, oooooooo lol winos applause please, also, found in raw peanuts, peanut butter, red grapes skins, cocoa powder)
A recent study in mice utilizing CRISPR to clear away these zombies increase their lifespan by 30%